FIELD: medicine. SUBSTANCE: method involves determining peptide level in patient saliva. The value being found equal to or greater than 0.882 optical density units, peptic ulcer disease exacerbation stage is considered to be the case. The value being found within the limits of 0.881 - 0.539 optical density units, peptic ulcer disease incomplete remission stage is considered to be the case. The value being found within the limits of 0.538 - 0.359 optical density units, stable remission stage is considered to be the case. EFFECT: simplified, reliable non-invasive method. 1 tbl