Composition comprising a combination of DNA methylation inhibitor and a vitamin D receptor agonist for the treatment of drug resistant cancer or for the prevention of tumor relapse
Institut National de la Sante et de la Recherche Medicale (INSERM);Centre National de la Recherche Scientifique (C.N.R.S.);Universite Paris Descartes;Foundation Imagine;Universite Paris Diderot—Paris 7;Universite Paris—Sud;Assistance Publique-Hopitaux de Paris (APHP)
The present invention concerns a combination of (i) a DNA methylation inhibitor, and (ii) a Vitamin D receptor agonist, for simultaneous or sequential use in the treatment of a drug resistant cancer and/or in prevention of tumor relapse in a patient suffering from cancer. The present invention also relates to a combination of (i) a DNA methylation inhibitor, and (ii) a Vitamin D receptor agonist, for increasing, restoring or enhancing sensitivity of a patient suffering from cancer to a chemotherapeutic drug in a patient suffering from cancer.
