COMPOSITION COMPRISING A COMBINATION OF DNA METHYLATION INHIBITOR AND A VITAMIN D RECEPTOR AGONIST FOR THE TREATMENT OF DRUG RESISTANT CANCER OR FOR THE PREVENTION OF TUMOR RELAPSE

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专利权人:

INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

发明人:

CRUZ-MOURA, IVAN,HERMINE, OLIVIER,PAUBELLE, ETIENNE,DUSSIOT, MICHAEL,TROVATI MACIEL, THIAGO,ZYLBERSZTEJN, FLORENCE

申请号：

CA2952898

公开号：

CA2952898A1

申请日:

2015.06.19

申请国别(地区):

CA

年份:

2015

代理人:

摘要：

The present invention concerns a combination of (i) a DNA methylation inhibitor, and (ii) a Vitamin D receptor agonist, for simultaneous or sequential use in the treatment of a drug resistant cancer and/or in prevention of tumor relapse in a patient suffering from cancer. The present invention also relates to a combination of (i) a DNA methylation inhibitor, and (ii) a Vitamin D receptor agonist, for increasing, restoring or enhancing sensitivity of a patient suffering from cancer to a chemotherapeutic drug in a patient suffering from cancer.

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