Composition comprising a combination of DNA methylation inhibitor and a vitamin D receptor agonist for the treatment of drug resistant cancer or for the prevention of tumor relapse
Ivan Cruz-Moura,Olivier Hermine,Etienne Paubelle,Michael Dussiot,Thiago Trovati Maciel,Florence Zylbersztejn
申请号:
US15320089
公开号:
US10111896B2
申请日:
2015.06.19
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention concerns a combination of (i) a DNA methylation inhibitor, and (ii) a Vitamin D receptor agonist, for simultaneous or sequential use in the treatment of a drug resistant cancer and/or in prevention of tumor relapse in a patient suffering from cancer. The present invention also relates to a combination of (i) a DNA methylation inhibitor, and (ii) a Vitamin D receptor agonist, for increasing, restoring or enhancing sensitivity of a patient suffering from cancer to a chemotherapeutic drug in a patient suffering from cancer.