MARION, Frédéric,ANNEREAU, Jean-Philippe,FAHY, Jacques
申请号：
ES09781165
公开号：
ES2584165T3
申请日:
2009.07.28
申请国别(地区):
ES
年份:
2016
代理人:
摘要：
Compound of the following general formula (I): or pharmaceutically acceptable salt thereof, an isomer or a mixture of isomers in all proportions, in particular a mixture of enantiomers, and in particular a racemic mixture, in which: - R1 represents a hydrogen atom or a linear or branched C1 to C6 alkyl group, - R2 represents a hydrogen atom, a saturated or unsaturated hydrocarbon cycle of 5 or 6 links, a linear or branched C1 to C6 alkyl group, arylalkyl, C (O) R ', SO2-R', C (O) OR ', or C (O) NHR', in which R 'represents a saturated or unsaturated hydrocarbon cycle of 5 or 6 links, a linear or branched alkyl group in C1 to C6, optionally substituted aryl, arylalkyl or heretoaryl, and - R3, R4, R5, R6 and R7 represent a hydrogen atom, in which: - an optionally substituted aryl group is a phenyl or naphthyl group, preferably a group phenyl, optionally substituted by one or more groups selected from: a halogen atom, an optionally substituted polyamine, a linear or branched C1 to C6 alkyl, a linear or branched C1 to C6 haloalkyl, -CN, -NO2, -OA4, -SO2A4, -NA5A6 and - (linear or branched alkyl in C1 to C6) -NA5A6 with: A4 representing a hydrogen atom or a linear or branched alkyl group in C1 to C6, A5 and A6 representing, independently from each other, a hydrogen atom, a linear or branched alkyl group in C1 to C6 or a saturated or unsaturated hydrocarbon cycle of 3 to 7 links, or A5 and A6 that together form, with the nitrogen atom bearing them, a 3 to 7 link heterocycle, saturated or unsaturated, which may comprise 1 to 3 additional heteroatoms, and optionally substituted with a linear or branched C1 to C6 alkyl group, and an optionally substituted polyamine having the formula: - [(CH2) a-NA1] d - [(CH2) b-NA2- ( CH2) c-NA3] eH, with a, b and c representing, independently of each other, a whole number purchased between 1 and 5； d and e each representing 0 or 1； and A1, A2 and A3, different or preferably identical, representing a hydrogen atom or a N-protecting group s
