APPLICATION OF HISTONIC DEACETHYLASE INHIBITORS TO IMPROVE IMMUNOTHERAPY

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专利权人:

ИНДИАНА ЮНИВЕРСИТИ РИСЕРЧ ЭНД ТЕКНОЛОДЖИ КОРПОРЕЙШН (US)

发明人:

ПИЛИ, Роберто (US)

申请号：

RU2018130831

公开号：

RU2018130831A

申请日:

2017.01.27

申请国别(地区):

RU

年份:

2020

代理人:

摘要：

Compositions including combinations of class I histone deacetylase (HDAC) inhibitors and programmed cell death protein 1 (PD-1) inhibitors for enhancing antitumor activity are disclosed. Further disclosed are methods of administering these compositions as immunotherapies for suppressing regulatory T cells in renal cell carcinoma.

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