A Compound represented by the following general formula (1),salts thereof or hydrates of the foregoing is a novel compound which maybe useful for treatment and/or prevention of diseases associated withthrombus formation, and which is safer with suitable physicochemicalstability.(see formula 1)[wherein R1a, R1b, R1c and R1d each independently represent hydrogen, etc.;R2 represents optionally substituted phenyl, etc.; R3 represents optionallysubstituted C6-10 aryl, etc.; and Z1 and Z2 each independently representhydrogen]