The invention relates to a drug composition to be applied topically for promoting the regeneration of tissue, characterized in that it contains microparticles from blood cells and/or tissues which have been purified by differential centrifugation, filtration or affinity chromatography, it has been subjected to a procedure for virus inactivation and/or virus depletion, it has been prepared under sterile conditions, and it is provided in freeze-dried or deep-frozen state.