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NON-IONIC AND THERMORESPONSIVE DIBLOCK COPOLYPEPTIDE HYDROGELS FOR DELIVERY OF MOLECULES AND CELLS
专利权人:
The Regents of the University of California
发明人:
Timothy J. Deming,Michael V. Sofroniew,Shanshan Zhang
申请号:
US15516211
公开号:
US20170296672A1
申请日:
2015.10.01
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention is directed to copolypeptide hydrogels (DCH) containing non-ionic hydrophilic residues (DCHEO), incorporation of thermoresponsive elements into DCHEO, to generate thermoresponsive DCH (DCHT), and hydrogels that include a combination of DCHEO and DCHT. The invention includes preparation, uses, compositions containing the hydrogels and methods of tuning the hydrogels. The hydrogels can be used to deliver an agent or cells to an organism.
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