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METHOD FOR MANUFACTURING COMPOSITION COMPRISING LOCAL ANESTHETIC HEPARINOID AND BUFFER
专利权人:
发明人:
PARSONS C LOWELL
申请号:
IN6300/CHENP/2013
公开号:
IN2013CN06300A
申请日:
2013.08.05
申请国别(地区):
IN
年份:
2014
代理人:
摘要:
An improved method for preparing a composition including a heparinoid a local anesthetic and a buffer for treatment of a lower urinary tract disease or condition can comprise: (i) providing a heparinoid in solid form or liquid form (ii) providing a local anesthetic in solid form or liquid form (iii) adding a liquid buffer to the heparinoid in solid form or liquid form (Iv) adding the local anesthetic to the mixture of the liquid buffer and the heparinoid and (v) if necessary adjusting the pH of the mixture of the liquid buffer the local anesthetic and the heparinoid so that a pH is achieved of from about 6.8 to about 8.3 is achieved without precipitation of the local anesthetic.
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