CYCLODEXTRINES AMMONIACALES QUATERNARISEES POUR UNE UTILISATION COMME AGENTS ANTIMICROBIENS, AGENTS DE CONSERVATION OU AGENTS D'AMELIORATION DE LA PENETRATION
KIS, GEORG LUDWIG,SCHOCH, CHRISTIAN,SZEJTLI, JOZSEF
申请号:
CA2487332
公开号:
CA2487332C
申请日:
2003.06.12
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
Use of a compound of formula (I), wherein the symbol (a) represents a n-valentresidue derived from a cyclodextrin compound by removing n of its hydroxylgroups; n is a number greater than 0 and represents the average number ofsubstituents of formula (II) per molecule of said compound; h is 0 or 1; R1 isa di-valent group selected from alkylene, hydroxy alkylene, halogeno alkylene,monocyclic aralkylene, cycloalkylene and phenylene; R2, R3 and R4 are eachindependently of one another a group selected from alkyl, cycloalkyl, aryl,aralkyl and cycloheteryl; Xm- is a m-fold negatively charged anion; m is aninteger being equal or greater than 1; and k is n/m in the preparation of ananti-infective medicament, as preservative and penetration enhancer.