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Spirochromanon derivatives
专利权人:
Merck Sharp & Dohme Corp.;MSD K.K.
发明人:
Niiyama, Kenji,Iino, Tomoharu,Yamakawa, Takeru,Shimamura, Tadashi,Jona, Hideki,Yang, Lihu,Nakamura, Masayuki,Shibata, Jun,Watanabe, Hitomi,Kurihara, Hideki
申请号:
AU2008205642
公开号:
AU2008205642B2
申请日:
2008.01.08
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
The invention relates to a compound of a general formula (I): wherein Ar1 representsa group formed from an aromatic ring selected from a group consisting of benzene,pyrazole, isoxazole, pyridine, indole, 1H-indazole, 1H-furo[2,3-c]pyrazole,1H-thieno[2,3-c]pyrazole, benzimidazole, 1,2-benzisoxazole, imidazo[1,2-a]pyridine,imidazo[1,5-a]pyridine and 1H-pyrazolo[3,4-b]pyridine, having Ar2, andoptionally having one or two or more substituents selected from R3; R1 and R2 eachindependently represent a hydrogen atom, a halogen atom, a cyano group, a C2-C6alkenyl group, a C1-C6 alkoxy group, a C2-C7 alkanoyl group, a C2-C7 alkoxycarbonylgroup, an aralkyloxycarbonyl group, a carbamoyl-C1-C6 alkoxy group, a carboxy-C2-C6alkenyl group, or a group of -Q1-N(Ra)-Q2-Rb; or a C1-C6 alkyl group optionallyhaving a substituent; or an aryl or heterocyclic group optionally having a substituent;or a C1-C6 alkyl group or a C2-C6 alkenyl group having the aryl or heterocyclicgroup; T and U each independently represent a nitrogen atom or a methine group;and V represents an oxygen atom or a sulfur atom. The compound of the inventionis useful as therapeutical agents for various ACC-related diseases.
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中国工程科技知识中心
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http://www.ckcest.cn/home/

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