Michael Anthony Cawthorne;Takashi Fujita;Hiroyoshi Horikoshi
发明人:
Takashi Fujita,Hiroyoshi Horikoshi,Michael Anthony Cawthorne
申请号：
US13696978
公开号：
US20130165446A1
申请日:
2011.05.11
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention addresses the problem of finding a compound having both PPAR activation activity and angiotensin receptor antagonistic activity. The present invention is a benzo- or pyrido-imidazole derivative represented by general formula (I), a pharmaceutically acceptable salt thereof, or a ester or amide thereof (where A is biphenyl methyl-imidazolyl, biphenyl methyl-benzimidazolyl, or the like, B is divalent benzimidazolyl or the like, C is carboxyl or the like, E is divalent phenyl, naphthyl, or the like, G is a dangling bond, oxygen, or the like, Q is oxygen or sulfur, n is an integer from 1 to 6, p is an integer from 1 to 6, V is a dangling bond, oxygen, or the like, and R is hydrogen, alkyl, or the like).
