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Benzo- or pyrido-imidazole derivative
专利权人:
Takashi Fujita;Hiroyoshi Horikoshi
发明人:
Fujita, Takashi,Horikoshi, Hiroyoshi,Cawthorne, Michael Anthony
申请号:
AU2011251302
公开号:
AU2011251302A1
申请日:
2011.05.11
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
Disclosed is a compound having both a PPAR activation action and an angiotensin receptor antagonistic action. Said compound is a benzo- or pyrido-imidazole derivative represented by expression (I) <;img file="JPOXMLDOC01-appb-I000261.tif" he="25.1" img-format="tif" wi="165.0"/>;, a pharmaceutically acceptable salt thereof or a pharmaceutically acceptable ester or amide thereof. (In the expression, A is a biphenyl methyl-imidazolyl group, biphenyl methyl-benzimidazolyl group, etc.; B is a divalent benzimidazolyl group, etc.; C is a carboxyl group, etc.; E is a divalent phenyl group, naphthyl group, etc.; G is a dangling bond, an oxygen atom, etc.; Q is an oxygen or sulfur atom; n is an integer from 1 to 6, p is an integer from 1 to 6; V is a dangling bond, an oxygen atom, etc.; and R is a hydrogen atom, an alkyl group, etc.)
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