Thomas Daniel Aicher,Zhaogen Chen,Ronald Jay Hinklin,Gary Alan Hite,Alexei Pavlovych Krasutsky,Renhua Li,Jefferson Ray McCowan,Ashraf Saeed,Nancy June Snyder,James Lee Toth,Owen Brendan Wallace,Leonar
申请号：
US12297349
公开号：
US08088776B2
申请日:
2007.04.19
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention discloses novel compounds of Formula I: possessing 11 β-HSD type 1 antagonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula I, as well as methods of using the compounds and compositions to treat diabetes, hyperglycemia, obesity, hypertension, hyperlipidemia, metabolic syndrome, cognitive disorders, and other conditions associated with 11 β-HSD type 1 activity.
