The Board of Trustees of the Leland Stanford Junior University
发明人:
Lin Michael,Chu Jun,Oh Younghee
申请号:
US201615197772
公开号:
US9908918(B2)
申请日:
2016.06.30
申请国别(地区):
美国
年份:
2018
代理人:
摘要:
Engineered orange-red fluorescent proteins with enhanced fluorescent properties, obtained by mutagenesis of mNeptune2, are disclosed. In particular, the invention relates to engineered orange-red fluorescent proteins excitable with cyan light having increased emission intensity and their use in bioluminescent resonance energy transfer systems and fluorescence and bioluminescence imaging.