USE OF MUTANT HERPES SIMPLEX VIRUS-2 FOR CANCER THERAPY

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专利权人:

THE UNIVERSITY OF HOUSTON

发明人:

ZHANG, Xiaoliu,張小柳,FU, Xinping,付新平

申请号：

HK16111798.3

公开号：

HK1223648A

申请日:

2016.10.12

申请国别(地区):

HK

年份:

2017

代理人:

摘要：

The present invention is directed to the composition and use of a modified Herpes Simplex Virus Type 2 (HSV-2) as a medicament in the treatment of cancer. The modified HSV-2 has fusogenic activity, and comprises a modified/mutated ICP 10 polynucleotide encoding a polypeptide having ribonucleotide reductase activity and lacking protein kinase activity.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/