Use of mutant Herpes Simplex Virus-2 for cancer therapy

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专利权人:

Xiaoliu Zhang

发明人:

Xiaoliu Zhang,Fu Xinping

申请号：

US11922796

公开号：

US08986672B2

申请日:

2006.06.23

申请国别(地区):

US

年份:

2015

代理人:

摘要：

The present invention is directed to the composition and use of a modified Herpes Simplex Virus Type 2 (HSV-2) as a medicament in the treatment of cancer. The modified HSV-2 has fusogenic activity, and comprises a modified/mutated ICP 10 polynucleotide encoding a polypeptide having ribonucleotide reductase activity and lacking protein kinase activity.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/