MARTIN ANDREAS FOLGER,BERNHARD HASSEL,STEFAN HENKE,JENS SCHMALZ
申请号：
IN7624DEN2014
公开号：
IN7624DEN2014A
申请日:
2014.09.12
申请国别(地区):
IN
年份:
2015
代理人:
摘要：
Fluid-bed granulation process comprising the steps: a) an aqueous solution of pimobendan and a binder is sprayed onto a solid support comprising one or several carriers and/or excipients, flavor and citric acid anhydrous and b) the mixture of a) is dried and c) the mixture of b) is sieved and de-agglomerated and d) a flow regulator is added to the mixture of c) and e) a lubricant is added to the mixture of d) and f) the mixture of e) is blended for uniformity of granules to obtain final 5 granules and/or g) the final granules off) are compressed to tablets.
