Virus de Dengue chimérique recombiné rDEN3/4delta 30(ME), rDEN2/4delta30(ME) ou rDEN1/4delta30(ME) contenant une déletion de 30 nucléotides (delta30) dans une part de la region non traduit 3' du génome du virus de Dengue type 4, la-dite déletion de 30 nucleotides correspondant à la structure du TL2 stem-loop.
The Government of the United States of America; as represented by the Secretary; Department of Health and Human Services
发明人:
申请号:
EP10177735.7
公开号:
EP2338508B1
申请日:
2003.04.25
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
A rDEN3/4”30(ME), rDEN2/4”30(ME) or rDEN1/4”30(ME) recombinant chimeric dengue virus containing a 30 nucleotide deletion (”30) in a section of the 3' untranslated region of dengue type 4 genome, where said 30 nucleotide deletion corresponds to the TL2 stem-loop structure.