A ROBUST BIO-CATALYTIC METHODOLOGY TO SYNTHESIZE (2E)-BUT-2-ENOATE COMPOUNDS USING LIPASE AND SUPERCRITICAL CARBON DIOXIDE AS A GREENER REACTION SYSTEM.

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专利权人:

发明人:

BADGUJAR KIRTIKUMAR CHANDULAL,BHANAGE BHALCHANDRA MAHADEO

申请号：

IN201621043666

公开号：

IN201621043666A

申请日:

2016.12.21

申请国别(地区):

IN

年份:

2016

代理人:

摘要：

The present invention offers an efficient green protocol for the synthesis of novel alkyl (2E)-but-2-enoate compounds in the SC-CO2 reaction media. This invention has various benefits like use of bio-catalyst and reaction solvent which fulfilled a complete green chemistry features. Furthermore, the present invention reports an efficient method for the synthesis of wide variety of (2E)-but-2- enoate compounds with extensive substrate array. The reaction protocol used is very simple, recyclable and appropriate for scale-up/ commercialization process which involves the simple work-up process to get desired product. This protocol offers excellent yield of desired products. FIGURE: Nil

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