CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
发明人:
CUNIN, FRÉDÉRIQUE,DURAND, JEAN-OLIVIER,SAILOR, MICHAEL J.,GARCIA, MARCEL,SECRET, EMILIE,GARY-BOBO, MAGALI,MAYNADIER, MARIE,MORERE, ALAIN
申请号:
EP13716977.7
公开号:
EP2831081A1
申请日:
2013.03.26
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
Disclosed are nanovectors of formula (I) that can be used simultaneously for the targeting, imaging and treatment, by photodynamic therapy, of cancer cells, and to biodegradable silicon nanoparticles containing a variety of photosensitizing molecules, in particular porphyrins, capable of targeting diseased cells and inducing cell death by excitation in the near-infrared region (>600 nm) in monophotonic and biphotonic modes. In formula (I), (AA) is a porous silicon nanoparticle.