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Functionalized porous silicon nanoparticles and use thereof in photodynamic therapy
专利权人:
发明人:
Frederique Cunin,Jean-Olivier Durand,Michael J. Sailor,Marcel Garcia,Emilie Secret,Magali Gary-Bobo,Marie Maynadier,Alain Morere
申请号:
US14388860
公开号:
US09694074B2
申请日:
2013.03.26
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Disclosed are nanovectors of formula (I) that can be used simultaneously for the targeting, imaging and treatment, by photodynamic therapy, of cancer cells, and to biodegradable silicon nanoparticles containing a variety of photosensitizing molecules, in particular porphyrins, capable of targeting diseased cells and inducing cell death by excitation in the near-infrared region (>600 nm) in monophotonic and biphotonic modes. In formula (I), (AA) is a porous silicon nanoparticle.
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http://www.ckcest.cn/home/

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