Martin ROBITAILLE,Karen THIBAUDEAU,Pierre LAURIN,Stacy PLUM
申请号：
US15771454
公开号：
US20190231854A1
申请日:
2016.11.03
申请国别(地区):
US
年份:
2019
代理人:
摘要：
Subjects of the invention are a method of plasminogen supplementation in a plasminogen-deficient subject, and method for the treatment of plasminogen-deficiency in a plasminogen-deficient subject. These methods comprise administering to the plasminogen-deficient subject a dose of plasminogen, and more particularly Glu-plasminogen, for increasing the subject plasminogen activity level by at least about 1%, and more particularly by at least about 10%, of the normal plasminogen activity and for maintaining said increased plasminogen activity level over a supplementation period or a treatment period. The plasminogen-deficient subject of the present invention may suffer from Type-I, Type-II plasminogen-deficiency or an acquired deficiency.
