Trawick, Bobby N.,Berberich, David W.,Grote, Christopher W.
申请号：
AU2010357625
公开号：
AU2010357625A1
申请日:
2010.12.22
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
The present invention provides (+)-morphinans comprising Toll-like receptor 9 (TLR9) antagonist activity, as well as methods for using the (+)-morphinans to treat pain. Also provided are pharmaceutical combination compositions comprising a (+)-morphinan and an opioid agonist/monoamine reuptake inhibitor, as well as methods for using the combination compositions to treat pain.
