Hsing-Wen Sung,Kiran Sonaje,Ho-Ngoc Nguyen,Er-Yuan Chuang,Hosheng Tu
申请号:
US13373995
公开号:
US08192718B1
申请日:
2011.12.07
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The invention relates to a method for treating disorders or diseases of a tight junction comprising delivering a pharmaceutical composition of nanoparticles to the tight junction, wherein the nanoparticles consist of positively charged chitosan, a negatively charged substrate, optionally a zero-charge compound, and at least one bioactive agent for treating said disorders or diseases of the tight junction of an animal subject.