Hsing-Wen Sung,Ha Giang Thi Nguyen,Fang Yi Su,Er-Yuan Chuang,Zi-Xian Liao,Hosheng Tu
申请号:
US13723775
公开号:
US08574544B1
申请日:
2012.12.21
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The invention discloses a pharmaceutical composition of nanoparticles consisting of chitosan, a negatively charged substrate, and at least one bioactive agent that is encapsulated within cucurbiturils for oral delivery. The chitosan-based nanoparticles are characterized with a positive surface charge and enhanced permeability for oral drug delivery.