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New compound imidazopyridine
专利权人:
ONO PHARMACEUTICAL CO.; LTD.
发明人:
TAKEUCHI, JUN,INUKAI, TAKAYUKI,SAKAI, MASARU
申请号:
ES10789507
公开号:
ES2511065T3
申请日:
2010.06.16
申请国别(地区):
ES
年份:
2014
代理人:
摘要:
Compound represented by formula (I): ** Formula ** in which it represents a benzene ring or a naphthalene ring or a 6 to 10 membered monocyclic or bicyclic aromatic heterocycle; R1 represents a hydrogen atom, methyl group, trifluoromethyl group, difluoromethyl group, fluorine atom or chlorine atom; R2 represents a hydrogen atom, C1-10 alkyl group optionally substituted with 1 to 6 of R11, C2-10 alkenyl optionally substituted with 1 to 6 of R11, or C2-10 alkynyl optionally substituted with 1 to 6 of R11; R11 represents: (i) a halogen atom, (ii) OR8, in which R8 is (1) a hydrogen atom, (2) C1-3 alkyl group, (3) C1-3 haloalkyl group, (4) a C5-6 carbocycle, (5) a 5- to 6-membered heterocycle containing 1 to 2 nitrogen atoms, 1 oxygen atom and / or 1 optionally oxidized sulfur atom, or (6) C1-3 alkyl group substituted with a hydroxyl group, C1-3 alkoxy group or NR9R10, in which R9 and R10 each independently represent a hydrogen atom, C1-3 alkyl group or phenyl group, (iii) NR9R10, in which R9 and R10 represent , each independently, a hydrogen atom, a C1-3 alkyl group or a phenyl group, (iv) a C5-6 carbocycle optionally substituted with at least one selected from a halogen atom, an oxo group and a group methyl, or (v) a 3 to 10 membered heterocycle containing 1 to 4 nitrogen atoms, 1 to 2 oxygen atoms and / or 1 to 2 optionally oxidized sulfur atoms, optionally substituted entity with at least one group selected from a halogen atom, an oxo group and a methyl group; R3 represents a hydrogen atom, a methyl group or a fluorine atom; R4 represents a hydrogen atom, a C1-2 alkyl group, a C1-2 haloalkyl group or a halogen atom; R5 represents a hydrogen atom, a C1-3 alkyl group, a C1-3 haloalkyl group or a halogen atom; R6 represents a hydrogen atom, a C1-3 alkyl group, a C1-3 haloalkyl group or a halogen atom; R7 represents a hydrogen atom, a C1-4 alkyl group, an allyl group, a trichlorethyl group, a benzyl group, a phenacyl group, a p-methoxybenzyl group, a trityl group or a 2-
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