An endoscope (100) or other endoscopic instrument (100) is provided with multiple image sensors (214, 216, 218) incorporated into the distal tip (105, 106), each capturing a portion of the image provided from an optical imaging system (205). The output from the multiple sensors (214, 216, 218) is combined and manipulated into a single high resolution image (215) which can then be displayed to the user. A virtual horizon rotation feature is also provided which can rotate a displayed image within a combined field of view including data from the multiple image sensors. Various light directing element designs (212, 213, 222, 224, 402) are provided to direct image light to the multiple sensors (214, 216, 218).