An endoscope or other endoscopic instrument is provided with multiple image sensors incorporated into the distal tip, each capturing a portion of the image provided from an optical imaging system. The output from the multiple sensors is combined and manipulated into a single high resolution image which can then be displayed to the user. A virtual horizon rotation feature is also provided which can rotate a displayed image within a combined field of view including data from the multiple image sensors. Various light directing element designs are provided to direct image light to the multiple sensors.