PROBLEM TO BE SOLVED: To provide a new 3-(4-substituted alkyl-phenyl)-2-furancarboxylic acid derivative having an antagonism to a glucagon receptor, and a pharmaceutically acceptable salt of the derivative.SOLUTION: The present invention provides a compound represented by formula (I) or a pharmaceutically acceptable salt of the compound. In the formula, ring A represents a phenylene or the like R1 represents a (substituted) aryl group having 6 to 10 carbon atoms or the like R2 and R3 each represent a hydrogen atom or an alkyl group having 1 to 4 carbon atoms R4 represents a hydrogen atom, a halogen atom or the like R5 and R6 each represent a hydrogen atom, a halogen atom or the like X represents an NR7 or the like R7 represents a hydrogen atom or the like R8 represents a cyano group or a nitro group and n represents 1 or the like.COPYRIGHT: (C)2013,JPO&INPIT【課題】グルカゴン受容体に拮抗作用を有する新規な3-(4-置換アルキル-フェニル)-2-フランカルボン酸誘導体およびその薬学的に許容される塩の提供。【解決手段】下記式(I)で表される化合物、またはその薬学的に許容される塩。[式中、環Aは、フェニレン等;R1は、(置換)C6-10アリール基等;R2およびR3は、水素原子またはC1-4アルキル基;R4は、水素原子、ハロゲン原子等;R5およびR6は、水素原子、ハロゲン原子等Xは、NR7等であり;R7は、水素原子等;R8は、シアノ基またはニトロ基;nは、1等である。]【選択図】なし
