BONFANTI, JEAN-FRANCOIS,柏法兰,柏法蘭,ANDRIES, KOENRAAD JOZEF LODEWIJK,安纳德,安納德,JANSSENS, FRANS EDUARD,强法兰,強法蘭,SOMMEN, FRANCOIS MARIA,索克斯,索克斯,GUILLEMONT, JEROME EMILE GEORGES,库裘米,庫裘米,LACRAMPE, JEAN FERNAND A
申请号：
TW093139736
公开号：
TWI378926B
申请日:
2004.12.20
申请国别(地区):
TW
年份:
2012
代理人:
摘要：
This Hair Ming You Off Right whats breathing fusion virus Complex System are with inhibitory activity and with the amido-Ben And imidazoles Class of following formula(I)Its preceding Drug,N- oxides,Jia Cheng Which,Four Grade amine,Jin Genus Wrong close object Ji Li Bodyization Learn Iso Agencies forms,Wherein the Q Department As Ar1 or one or more Ge Election of Visual Qing Condition The are from trifluoromethyl,C3-7 Ring alkyl,Ar2,Hydroxyalkyl bases,C1-4 alkoxies,C1-4 alkylthio groups,Ar2- oxygroups-,Ar2- sulfenyls-,Ar2(CH2)N oxygroups-,Ar2(CH2)N sulfenyls-,Hydroxyalkyl base carbonyls,Amino-carbonyl,C1-4 alkyl-carbonyls,Ar2 carbonyls,C1-4 alkoxy carbonyl groups,Ar2(CH2)N carbonyls-,Amino-carbonyl oxygroup,C1-4 alkyl carbonyl epoxides,Ar2 carbonyl oxygroups,Ar2(CH2)N carbonyl oxygroups,Hydroxyalkyl base-C2-4 alkyl oxies,C1-4 alkoxy carbonyl groups(CH2)N oxygroups-,Single-or two(C1-4 alkyl)Amino-carbonyl,Single-or two(C1-4 alkyl)Amino-carbonyl oxygroup,Amido sulphur anilide,Single-or two(C1-4 alkyl)Amido sulphur anilide,The replaced Er Yang Wu Ring Ji of Visual Qing Condition The mono- or two Ge C1-6 alkyl Ji Election from pyrrolidinyl,Pyrrole radicals,Two Hydrogen pyrrole radicals,Thiazolidinyl,Imidazole radicals,Triazolyl,Six Hydrogen pyridyl groups,High six Hydrogen pyridyl groups,Piperazine bases,C1-6 alkyl replaced the substituent group of pyridyl group and four Hydrogen pyridyl group Miscellaneous Ring,Wherein The Miscellaneous Ring respectively can be replaced Visual Qing Condition The ketone groups or C1-6 alkylThe C1-10 alkane diyls of G Department As Zhi Jie Key Knot or Visual Qing Condition The substitutionsR1 Department As Ar1 Huo Single Ring Huo Twin Ring Miscellaneous RingIt is another in R2a and R3a Zhong Yi Department As C1-6 alkyl and R2a and R3aPerson As HydrogenIf non-Hydrogen , The R2b Department As Hydrogen or the C1-6 alkyl of R2a, and R3b Department As HydrogenIf non-Hydrogen , The R3b Department As Hydrogen or the C1-6 alkyl of R3a, and R2b
