LAMPILAS MAXIME,ROWLANDS DAVID ALUN,LEDOUSSAL BENOIT,GOURDEL MARIE EDITH,RENAUD EMILIE,PIERRES CAMILLE,KEBSI ADEL
申请号：
IN2394/DELNP/2011
公开号：
IN2011DN02394A
申请日:
2011.03.31
申请国别(地区):
IN
年份:
2012
代理人:
摘要：
R1 represents a (CH2)n-NH2 radical, n being equal to 1 or 2 R2 represents a hydrogen atom R3 and R4 form together a nitrogen-containing heterocycle with aromaticity with 5 apices containing 1, 2 or 3 nitrogen atoms, substituted on this nitrogen atom or one of these nitrogen atoms with a (CH2)m-(C (0) )P-R5 group, m being equal to 0, 1, 2 or 3, p being equal to 0 or 1 and R5 representing a hydroxy group, in which case p is equal to 1, or an amino, (C1-C6) alkyl or di- (C1-C6) alkyl amino, a nitrogen-containing heterocycle with aromaticity with 5 or 6 apices containing 1 or 2 nitrogen atoms and if necessary, an oxygen or sulfur atom it being understood that when the sub-group (C(0))p-R5 forms a carboxy, amino, (C1-C6) alkyl or di-(C1-C6) alkyl amino, group, m is different from 0 or 1 in free form or as zwitterions and salts with pharmaceutically acceptable mineral or organic bases and acids, to their preparation and to their use as antibacterial drugs.
