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AMORPHOUS ASIATIC TROMETHAMINE SALT AND PREPARATION METHOD THEREOF
专利权人:
SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY
发明人:
REN, GUOBIN,LIU, YING,CHEN, JINYAO,HUANG, XIAOLING,XIAO, LIN,CAI, LI,ZHANG, TIAN,WU, XUEJUN,SUN, HAIYAN,LIU, QUANHAI,JIN, LILING,LIU, MINYU,DENG, YIFANG,XU, ZHIRU,CHEN, RENHAI,LI, CHUNGANG,TAN, XIANGD
申请号:
EP12760240
公开号:
EP2711373A4
申请日:
2012.03.21
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
Disclosed are an amorphous asiatic tromethamine salt and the preparation method thereof. The method comprises the steps of: (1) dissolving asiatic acid in an organic solvent step (2) mixing with tromethamine step (3) stirring and salifying the same, and then removing the organic solvent. The method for preparing the amorphous asiatic tromethamine salt is easy and effective, and the water solubility and bioavailability of the asiatic tromethamine salt thus obtained are greatly compared with the prior art.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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