BAIR, Kenneth,LANCIA, David R.,LI, Hongbin,LOCH, James,LU, Wei,MARTIN, Matthew,MILLAN, David,SCHILLER, Shawn,TEBBE, Mark
申请号:
HUE14779048
公开号:
HUE045701T2
申请日:
2014.03.11
申请国别(地区):
HU
年份:
2020
代理人:
摘要:
The present invention relates to a list of specific 2-hydroxy-1-{4-[(4-phenylphenyl)carbonyl]piperazin-1-yl}ethan-1-one derivatives and related compounds as fatty acid synthase (FAS or FASN) inhibitors for treating cancer and pharmacutical compositions thereof .An illustrative compound of the invention is shown below: