Jidong Wang,Hui Zhang,Haibin Wang,Lingping Ying,Sheng Wang,Xufang Guan,Hua Bai
申请号：
US12865581
公开号：
US08906947B2
申请日:
2008.02.01
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The invention discloses a method for the separation and purification of epothilones, especially discloses a method for the separation and purification of epothilones B and A using normal phase silica gel chromatography, which comprises loading the sample after dissolving the sample containing epothilones B and A with C1-C7 alkyl halide compounds or mixing the sample with silica gel, then gradient eluting silica gel column by an elution solvent of normal phase silica gel column, and finally obtaining products.
