BROTHERTON-PLEISS, CHRISTINE, E. E-,CHEN, ZHI,ERICKSON, SHAWN, DAVID,KIM, KYUNGJIN,LI, HONG JU,QIAN, YIMIN,SO, SUNG-SAU,WOVKULICH, PETER, MICHAEL,YI, LIN,伊林,克里斯蒂娜‧,‧布拉澤頓-普里斯,陳智,肖恩‧戴維‧埃里克森,金慶鎮,李宏舉,錢義民,蘇松塞
申请号:
HK15108260.9
公开号:
HK1207634A
申请日:
2015.08.25
申请国别(地区):
HK
年份:
2016
代理人:
摘要:
The invention is concerned with the compounds of formula (I): and pharmaceutically acceptable salts thereof, wherein Y, R1, R2 and R3 are defined in the detailed description and claims. In addition, the present invention relates to methods of manufacturing and using the compounds of formula (I) as well as pharmaceutical compositions containing such compounds. The compounds of formula (I) are antagonists of the TRPA1 channel and may be useful in treating inflammatory diseases and disorders associated with that channel.