BROTHERTON-PLEISS, CHRISTINE E.,CHEN, ZHI,ERICKSON, SHAWN DAVID,KIM, KYUNGJIN,LI, HONGJU,QIAN, YIMIN,SO, SUNG-SAU,WOVKULICH, PETER MICHAEL,YI, LIN
申请号：
CA2885417
公开号：
CA2885417A1
申请日:
2013.10.09
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
The invention is concerned with the compounds of formula (I): and pharmaceutically acceptable salts thereof, wherein Y, R1, R2 and R3 are defined in the detailed description and claims. In addition, the present invention relates to methods of manufacturing and using the compounds of formula (I) as well as pharmaceutical compositions containing such compounds. The compounds of formula (I) are antagonists of the TRPA1 channel and may be useful in treating inflammatory diseases and disorders associated with that channel.
