USTAV ORGANICKE CHEMIE A BIOCHEMIE AKADEMIE VED CESKE REPUBLIKY;REGA STICHTING VZW.
发明人:
HOLY, ANTONIN,DE CLERCQ, ERIK, DESIRE, ALICE
申请号：
DK96909007
公开号：
DK0821690T3
申请日:
1996.04.19
申请国别(地区):
DK
年份:
2012
代理人:
摘要：
Novel PMP, PME and HPMP and related compounds containing N-6 substituted 2,6-diaminopurine and adenine bases are provided. These compounds are useful in a variety of utilities, including as intermediates in the preparation of flame retardants, diagnostic reagents and therapeutics, including antivirals. Of particular note are compounds otherwise not known to possess anti-DNA viral activity that become potent inhibitors of DNA viruses upon substitution of the N-6 site, thereby providing a novel and unexpected and surprising use for such compounds.
