Sunnie R. Thompson,Erik Mills Schwiebert,John H. Streiff
申请号:
US13259503
公开号:
US20120065247A1
申请日:
2010.03.26
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Provided herein are compounds and methods for use in preventing or treating a viral infection mediated by a virus comprising an IRES-containing RNA molecule or cancer related to an increase or decrease in IRES-mediated translation of an RNA molecule. Also provided are methods of inhibiting or promoting IRES-mediated translation. Also provided are methods of screening for an agent that inhibits IRES-mediated translation.