Shannon K. Oda,Philip D. Greenberg,Thomas M. Schmitt
申请号：
US15555951
公开号：
US20180044404A1
申请日:
2016.03.04
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present disclosure relates to immunomodulatory fusion proteins containing an extracellular binding domain and an intracellular signaling domain, wherein binding of a target can generate a modulatory signal in a host cell, such as a T cell. The present disclosure also relates to uses of immune cells expressing such immunomodulatory fusion proteins to treat certain diseases, such as cancer or infectious disease.
