The present invention relates to include the pet food or pet replenishers for cooperateing with effective anti-oxidant compositions, the anti-oxidant compositions include vinifera extract and narrow leaf cranberry extract, wherein the composition includes at least 1% catechin and/or the ferulic acid of epicatechin and at least 5ppm.The invention further relates to purposes of the effective anti-oxidant compositions as pet drug is cooperateed with, the purposes in method especially for treating pet Neurodegenerative conditions.