Germaine Fuh,Hans-Peter Gerber,Wei-Ching Liang,Frederic Fellouse,Sachdev S. Sidhu,Christian Wiesmann
申请号:
US13929338
公开号:
US08975381B2
申请日:
2013.06.27
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Anti-VEGF antibodies and variants thereof, including those having high affinity for binding to VEGF, are disclosed. Also provided are methods of using phage display technology with naïve libraries to generate and select the anti-VEGF antibodies with desired binding and other biological activities. Further contemplated are uses of the antibodies in research, diagnostic and therapeutic applications.