KIM, JIN CHEOL,김진철,KIM, JONG DAI,김종대,KANG, MI KYOUNG,강미경,SEO, HEE JIN,서희진
申请号：
KR1020100127677
公开号：
KR1020120066369A
申请日:
2010.12.14
申请国别(地区):
KR
年份:
2012
代理人:
摘要：
PURPOSE: A chitosan microgel for inclusion of a target material is provided to control release of the target matetial by responding to pH change.CONSTITUTION: A chitosan microgel contains chitosan which is crosslinked with gluta aldehyde, formaldehyde, or dextrin aldehyde. A method for preparing the chitosan microgel comprises: a step of dissolving the chitosan in an acid solution to prepare a chitosan solution a step of adding a crosslinking agent of gluta aldehyde, formaldehyde, or dextrin aldehyde into the chitosan solution a step of spray-drying a mixture solution of chitosan and crosslinking agent to prepare crosslinked chitosan microgel and a step of loading the target material on the chitosan microgel.COPYRIGHT KIPO 2012본 발명은 목적물질을 포접할 수 있는 키토산 마이크로겔로서 키토산이 글루타알데히드, 포름알데히드 및 덱스트린알데히드로 이루어진 군에서 선택된 하나 이상으로 가교되어 pH 변화에 응답하여 목적물질 방출을 조절할 수 있는 특징이 있다.
