PROBLEM TO BE SOLVED: To provide a method for producing a ground product with suppressed attachment of powder to a crushing machine and excellent elution of a medicine.SOLUTION: A method for producing a ground product has the step of applying crushing treatment to a mixture containing following (A) component and (B) component. In the mixture, the mass percentage of the (B) component, represented by the (B) component/(the (A) component+the (B) component)×100, is 5-25 mass%. (A) component: a poorly water-soluble medicine with a melting point of 250°C or lower and (B) component: water at 0°C or lower.SELECTED DRAWING: NoneCOPYRIGHT: (C)2019,JPO&INPIT【課題】粉砕機への粉体の付着を抑制し、薬物の溶出性が良好な粉砕物の製造方法。【解決手段】下記(A)成分及び(B)成分を含有する混合物に粉砕処理を施す工程を有し、前記混合物は、前記(B)成分/(前記(A)成分+前記(B)成分)×100で表される前記(B)成分の質量百分率が、5~25質量%である、粉砕物の製造方法。(A)成分:融点が250℃以下の水難溶性薬物。(B)成分:0℃以下の水。【選択図】なし
