PROBLEM TO BE SOLVED: To provide a semisolid formulation that contains a poorly water-soluble medicine and has high heat stability.SOLUTION: A semisolid formulation contains (A) a poorly water-soluble medicine, (B) mannitol, (C) a gelator, and (D) water, with the mass of (D) component of 50 mass% or less relative to the total mass of the semisolid formulation. The mass ratio represented by (B) component/(A) component is preferably 0.001-0.15.SELECTED DRAWING: NoneCOPYRIGHT: (C)2018,JPO&INPIT【課題】水難溶性薬物を含有し、かつ熱安定性の高い半固形製剤。【解決手段】(A)水難溶性薬物、(B)マンニトール、(C)ゲル化剤、及び(D)水を含有し、半固形製剤全体の質量に対する前記(D)成分の質量が50質量%以下である、半固形製剤。前記(B)成分/前記(A)成分で表される質量比は0.001~0.15であることが好ましい。【選択図】なし
