14-0-[(((C1.6)Alkoxy-(C1.6)alkyl)-phenylsulfanyl)-acetyl]-mutilins, 14-O-[(((C1-6)Mono- or dialkylamino-(C1.6)alkyl)-phenylsulfanyl)-acetyl]-mutilins,14-O-[((Hydroxy-(C1-6)-alkyl)-phenylsulfanyl)-acetyl]-mutilins, 14-O-[((Formyl-(C0.5)-alkyl)-phenylsulfanyl)-acetyl]-mutilins, 14-O-[((Guanidino-imino-(C1-6)alkyl)-phenylsulfanyl)-acetyl]-mutilins, 14-O-[((Ureido-imino-(C1-6)alky)-phenylsulfany]-acety]-mutilins, 14-O-[((Thioureido-imino-(C1-6)alkyl)-phenylsulfanyl)-acetyl]-mutilins, 14-O-[((lsothioureido-imino-(C1-6)alkyl)-phenylsulfanyl)-acetyl]-mutilins and their use as pharmaceuticals.