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פלאורומוטילינים, תכשירים רפואים המכילים אותם ושימושם בהכנת תרופות לטיפול, במיוחד לטיפול באקנה
专利权人:
NABRIVA THERAPEUTICS AG
发明人:
申请号:
IL19275608
公开号:
IL192756A
申请日:
2008.07.10
申请国别(地区):
IL
年份:
2015
代理人:
摘要:
14-O-[(((C 1-6 )Alkoxy-(C 1-6 )alkyl)-phenylsulfanyl)-acetyl]-mutilins, 14-O-[(((C 1-6 )Alkylthio-(C 1-6 )alkyl)-phenylsulfanyl)-acetyl]-mutilins, 14-O-[(((C 1-6 )Mono- or dialkylamino-(C 1-6 )alkyl)-phenylsulfanyl)-acetyl]-mutilins. 14-O-[((Hydroxy-(C 1-6 )-alkyl)-phenylsulfanyl)-acetyl]-mutilins, 14-O-[((Formyl-(C 0-5 )-alkyl)-phenylsulfanyl)-acetyl]-mutilins,14-O-[((Guanidino-imino-(C 1 - e )alkyl)-phenylsulfanyl)-acetyl]-mutilins, 14-O-[((Ureido-imino-(C 1-6 )alkyl)-phenylsulfanyl)-acetyl]-mutilins, 14-O-[((Thioureido-imino-(C 1-6 )alkyl)-phenylsulfanyl)-acety]-mutilins, 14-O-[((Isothioureido-imino-(C 1-6 )alkyl)-ph enylsulfanyl)-acetyl]-mutilins, 14-O-[(((C 1-8 )Alkoxy-(C 1-6 )alkyl)- 5- or 6-membered heteroarylsulfanyl)-acetyl]-mutilins, 14-O-[((Hydroxy-(C 1-6 )-alkyl)-5- or 6-membered heteroarylsulfanyl)-acetyl]-mutilins, 14-O-[((Formyl-(C 0-6 )-alkyl)- 5- or 6-membered heteroarylsulfanyl)-acetyl]-mutilins, 14-O-[((Guanidino-imino-(C 1-6 )alkyl)- 5- or 6-membered heteroarylsulfanyl)-acetyl]-mutilins, 14-O-[(C 1-6 )Alkylguanidino-imino-(C 1-6 )alkyl)-5- or 6-membered heteroarylsulfanyl)-acetyl]-mutilins, 14-O-[((Ureido-imino-(C 1-8 )alkyl)- 5- or 6-membered heteroarylsulfanyl)-acetyl]-mutilins, 14-O-[Thioureido-imino-(C 1-6 )alkyl)- 5- or 6-membered heteroarylsulfanyl)-acetyl]-mutilins, 14-O-[((Isothioureido-imino-(C 1-6 )alkyl)- 5-or 6-membered heteroarylsulfanyl)-acetyl]-mutilins and their use as pharmaceuticals.
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