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СПОСОБ ПРОГНОЗИРОВАНИЯ РАЗВИТИЯ МУЛЬТИФАКТОРНОЙ ПАТОЛОГИИ У ДЕТЕЙ, РОЖДЕННЫХ С ПОМОЩЬЮ ВСПОМОГАТЕЛЬНЫХ РЕПРОДУКТИВНЫХ ТЕХНОЛОГИЙ
专利权人:
GOSUDARSTVENNOE UCHREZHDENIE ZDRAVOOKHRANENIJA SVERDLOVSKOJ OBLASTI DETSKAJA KLINICHESKAJA BOLNITSA VOSSTANOVITELNOGO LECHENIJA "NAUCHNO-PRAKTICHESKIJ TSENTR "BONUM"
发明人:
PLAKSINA ANNA NIKOLAEVNA,Плаксина Анна Николаевна (RU),MARCHUK JURIJ VLADIMIROVICH,Марчук Юрий Владимирович (RU),KOVTUN OLGA PETROVNA,Ковтун Ольга Петровна (RU),BLOKHINA SVETLANA IVANOVNA,Блохина Свет
申请号:
RU2011108890/14
公开号:
RU0002456911C1
申请日:
2011.03.09
申请国别(地区):
RU
年份:
2012
代理人:
摘要:
FIELD: medicine.SUBSTANCE: method relates to medicine, namely to neonatology, hematology, pediatrics and makes it possible to predict risk of development of multifactor pathology in children, born with application of auxiliary reproductive technologies in families with syndrome of fetus loss. Medical history and clinical signs are analysed and estimated in ante-. Intra- and neonatal periods of childs life, in ante- and intranatal periods determined are: X1 - presence of anemia in mother during pregnancy, X2 - presence of threat of current pregnancy abortion, X3 - presence of chronic feto-placental failure, X4 - presence of gestosis, X5 - delivery by cesarean section in neonatal period of childs life determined are: X6 - staying of child in room of intensive care or resuscitation, X7 - transfer into therapeutic prophylactic establishment, X8 - administration of antibacterial therapy, X9 - delayed vaccination, X10 - administration of infusion therapy, X11 - administration of parenteral feeding, X12 - administration of blood preparations, X13 - estimation of childs state by Algar scale at 1 minute of life, and values of discriminate functions Y1 and Y2 are calculated by formulae: Y1=-136.805+11.123*X1+15.622*X2+16.737*X3+10.728*X4+8.285*X5+44.296*X6-15.549*X7+27.818*X8-16.443*X9+5.231*X10-28.815*X11+24.319*X12+23.134*X13 Y2=172.87+13.898*X1+22.385*X2+23.460*X3+15.047*X4+8.820*X5+35.859*X6-3.348*X7+19.418*X8-13.431*X9+18.444*X10-39.685*X11+28.512*X12+22.949*X13, where Y1 is discriminate function of group of children who have low predisposition to development of multifactor pathology, Y2 is discriminate function of group of children who have high risk of development of multifactor pathology, X1, X2, …, X13 are values of clinical-medical history signs, in case is signs X1-X12 are present, they are evaluated in 2 points, if they are absent - as 1 point X13 is estimation in points by Algar scale -136.805 and -172.87 are free members, and if value of Y2 function is larger th
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