The United States of America, as represented by The Secretary, Department of Health and Human Services
发明人:
BEWLEY, Carole, A.,PLAZA, Alberto,KEFFER, Jessica
申请号:
EP20110748136
公开号:
EP2539305(B1)
申请日:
2011.02.25
申请国别(地区):
欧洲专利局
年份:
2017
代理人:
摘要:
Embodiments of antimicrobial chrysophaentin compounds, pharmaceutical compositions including the chrysophaentin compounds, and methods for using the chrysophaentin compounds are disclosed. Some embodiments of the disclosed compounds are isolated from Chrysophaeum taylori. Certain embodiments of the chrysophaentin compounds inhibit FtsZ protein, thereby inhibiting the growth of clinically relevant bacteria, including drug-resistant strains.